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Author Topic: Plastic and stimulus-specific coding of salient events in the central amygdala  (Read 1179 times)

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Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC10665639/

Plastic and stimulus-specific coding of salient events in the central amygdala

Terminology:

Central Amygdala = 'CeA'

Somatostatin expressing = Sst+ neurons mediate much of CeA functions.

**Somatostatin** is a peptide hormone that plays a crucial role in regulating various bodily functions by inhibiting the release of hormones and theirr secretion including growth hormone, thyroid-stimulating hormone, insulin, glucagon and other hormones.
 
Abstract:

The central amygdala (CeA) is implicated in a range of mental processes including attention, motivation, memory formation and extinction, and in behaviors driven by either aversive or appetitive stimuli.

How it participates in these divergent functions remains elusive.

Somatostatin-expressing (Sst+) CeA neurons mediate much of CeA functions, generate experience-dependent and stimulus-specific evaluative signals essential for learning.

The population responses of these neurons in mice encode the identities of a wide range of salient stimuli, with the responses of separate subpopulations selectively representing the stimuli that have contrasting valences, sensory modalities, or physical properties (e.g., shock and water reward).

This paper continues at the source link ...

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