dopetalk does not endorse any advertised product nor does it accept any liability for it's use or misuse

This website has run out of funding so feel free to contribute if you can afford it (see footer)

Author Topic: Temazepam withdrawal in elderly patients comparing abrupt versus gradual  (Read 5969 times)

Offline Chip (OP)

  • Server Admin
  • Hero Member
  • *****
  • Administrator
  • *****
  • Join Date: Dec 2014
  • Location: Australia
  • Posts: 6651
  • Reputation Power: 0
  • Chip has hidden their reputation power
  • Gender: Male
  • Last Login:June 17, 2024, 01:21:57 PM
  • Deeply Confused Learner
  • Profession: IT Engineer
it's time to ditch the Temaz for quite a while and whilst researching, I encountered this encouraging quick study from 1989:

source: https://www.ncbi.nlm.nih.gov/pubmed/2576423

Temazepam withdrawal in elderly hospitalized patients: a double blind randomised trial comparing abrupt versus gradual withdrawal

Abstract

31 of 36 elderly mainly confused hospitalized patients (69-98 years) taking temazepam 10 mgs nocte for more than one month completed a double blind randomised placebo controlled trial comparing abrupt versus gradual withdrawal of temazepam.

Hours of sleep were recorded for all patients during a 7 day baseline period while taking temazepam 10 mg nocte.

Then the abrupt withdrawal (AW) group (n = 15) received placebo for 10 nights and the gradual withdrawal (GW) group (n = 16) received temazepam 5 mg for the first 4 nights, 2 mg for the next 4 nights and placebo for the last 2 nights.

There was no significant difference in mean hours of nightly sleep during the baseline period between the AW group (5.9 +/- 1.1 SD) and GW group (5.8 +/- 1.1 SD) and between the baseline and withdrawal periods in each group (withdrawal periods, AW 5.6 +/- 1.2, GW 5.6 +/- 1.0).

There was no rebound insomnia when temazepam was withdrawn either abruptly or gradually in long-term hospitalised elderly patients and may not be effective as a long-term hypnotic.

friendly
0
funny
0
informative
0
agree
0
disagree
0
like
0
dislike
0
No reactions
No reactions
No reactions
No reactions
No reactions
No reactions
No reactions
Our Discord Server invitation link is https://discord.gg/jB2qmRrxyD

Tags:
 

Related Topics

  Subject / Started by Replies Last post
0 Replies
6243 Views
Last post October 19, 2016, 12:36:35 PM
by Chip
4 Replies
9528 Views
Last post February 08, 2018, 08:08:07 PM
by Chip
3 Replies
7420 Views
Last post September 02, 2017, 10:06:18 AM
by Chip
2 Replies
8376 Views
Last post February 08, 2018, 06:10:23 PM
by DreamerOnTheRun
2 Replies
6893 Views
Last post April 12, 2019, 08:44:54 PM
by Joseph Hopeless
1 Replies
7006 Views
Last post May 02, 2019, 04:56:27 PM
by Chip
0 Replies
4926 Views
Last post May 28, 2019, 07:28:18 AM
by Chip
0 Replies
4456 Views
Last post October 23, 2019, 11:20:58 AM
by Chip
1 Replies
7543 Views
Last post January 12, 2024, 04:20:10 PM
by Chip
0 Replies
3886 Views
Last post January 17, 2024, 05:45:07 PM
by Chip


dopetalk does not endorse any advertised product nor does it accept any liability for it's use or misuse





TERMS AND CONDITIONS

In no event will d&u or any person involved in creating, producing, or distributing site information be liable for any direct, indirect, incidental, punitive, special or consequential damages arising out of the use of or inability to use d&u. You agree to indemnify and hold harmless d&u, its domain founders, sponsors, maintainers, server administrators, volunteers and contributors from and against all liability, claims, damages, costs and expenses, including legal fees, that arise directly or indirectly from the use of any part of the d&u site.


TO USE THIS WEBSITE YOU MUST AGREE TO THE TERMS AND CONDITIONS ABOVE


Founded December 2014
SimplePortal 2.3.6 © 2008-2014, SimplePortal