🍺 Alcohol Harm Minimisation StackUser profile: ~20 standard drinks/week
Goal: Protect liver, brain, mood, and mitochondria from ethanol exposure.
🧠 Core Daily Supplements- NAC (N-acetylcysteine): 600β1200 mg 1β2x/day β boosts glutathione; protects liver 🛡οΈ
- B-Complex (active forms): High-potency β replaces depleted B1, B6, B12, folate 💊
- Magnesium (glycinate or threonate): 200β400 mg β CNS calming, helps sleep and GABA 💤
- ALA (Alpha Lipoic Acid): 300β600 mg β antioxidant and mitochondrial support 🔋
- Vitamin C: 1000 mg β antioxidant; helps detox 🍊
- Milk Thistle (Silymarin): 300β600 mg β proven liver support 🌿
- Taurine: 500β1000 mg β supports bile, liver, and calming β‘
- Zinc (Picolinate or Bisglycinate): 25β50 mg β immune and liver cofactor 🛠οΈ
β οΈ Optional / Cycled (2β3x per week or on drinking days)- TUDCA: 250β500 mg β bile flow + membrane protection
- Curcumin (Meriva/Longvida): 500β1000 mg β anti-inflammatory and neuroprotective 🧠
- CoQ10 or Ubiquinol: 100β200 mg β mitochondria + heart health β€οΈ
- DHM (Dihydromyricetin): 300β600 mg β anti-hangover; helps liver enzymes 🍃
💧 Behavior Tips- Use electrolytes before and after drinking (coconut water + salt).
- Avoid paracetamol (acetaminophen) when drinking β it's liver toxic.
- Eat protein + fat before alcohol to slow absorption.
- Activated charcoal (1β2g) only AFTER final drink, if bloated.
- Liver function tests (LFTs) are recommended every few months.
β
Optional Add-ons- Broccoli sprouts / Sulforaphane β activates detox genes (NRF2)
- Resveratrol β NAD+ preservation, antioxidant
- Choline or CDP-Choline β combats brain fog
🧪 This stack wonβt make alcohol safe, but itβs your biochemical armour if youβre drinking regularly.