Neurodegenerative Disorder Treatment Thoughts

[Chip (OP)]

To: info@mndaustralia.org.au,
info@mndnsw.asn.au,
info@mndvic.org.au,
info@mndqld.org.au,
info@mndresearch.org.au,
info@mndcare.org.au,
info@naa.org.au,
info@aihw.gov.au,
mndresearch@unimelb.edu.au,
neuroscience.research@sydney.edu.au,
enquiries@florey.edu.au,
aegersz@gmail.com

Dear Health Professionals,

I want nothing except your consideration on this matter and you were recommended to me.

My background is in Large Systems and I'm running a few AI systems to verify my thoughts and now I defer to the trained.

* Phase 1:

A. Get a Lipidomic profile, if possible.

B. Check genetic markers for autoimmune disease.

C. Compound/Swallow:

1. L-Methionine 500-2000 mg
with
2. SAMe
with
3. Methyl B12
with
4. NAC 600-1200 mg
with
5. 1000 mg Ascorbic acid
with
6. Acetyl-CoA

D.Treat for 3 months

E. Repeat 0. for another Lipidomic profile ?

F. Compare with D. against B. and

G. Is there a satisfactory improvement ?

Yes - Keep treating

H. No - Check the genome's genetic markers for autoimmune disease / this disorder.

Intercept *Histone process* dor Epigenetic Gene Edit and start silencing/activating the most debilitating genetic markers with CRISPR/CAS9~CAS13.

Goal: Target specific gene expressions related to inflammation, neurodegeneration, or motor neuron function by modifying epigenetic markers.

Feasibility: Epigenetic editing with CRISPR/Cas technology is still in experimental stages for complex diseases like MND, particularly in neurons.

While it’s an exciting frontier, safety and specificity challenges remain, especially for conditions where multiple genes are involved.

This structured approach provides a mix of metabolic support, genetic assessment, and advanced therapeutic goals.

* Phase 2 - Consider one of more of the following therapies:

1. CDP-Choline
for synapse support.

2. L-Dopa
for Parkinson’s but may help here too.

3. Methylphenidate - 10 mg
standalone or to offset the Zolpidem "option of last resort".

4. Nicotine Gum - 4 mg
to activate the NMJ or Neuro Muscular Junction.

5. L-Glutamine and GABA supplement
* try to stabilise the 15 Transporters in the Glutaminergic-GABAergic complex.

6. ECT
may resynchronise the Irregular neural oscillations.

7. Check all Reflexes, confirm local signalling is functional.

8. Stem cell therapies could help.

9. Resveratrol
Voltage Gated Calcium channel promoter.

10. Pregabalin
Voltage Gated Calcium channel blocker and nerve agent.

11. For more symptom acquisition try to inject Botox at signal attenuation point and report your observations.

12. SSRIs have proven to promote nerve growth through it action as a potent neuroplastic agent.

13. NGF (Nerve Growth Factor) therapy.

14. 👉 ZOLPIDEM Tartrate with trace doses of Flumazenil to emulate a psuedo-partial agonist like the "Targin of Z-drugs."

Yours faithfully,

Andrew Egerszegi