5-HTP experiences ?

[Chip (OP)]

5-Hydroxytryptophan^Wiki

About to get some delivered, in the past, 200 mg. with toast used to put me to sleep around bedtime, quite nicely.

Has anybody had any experience with this, like dosing or good/bad etc ?

I would welcome any input - Wiki says this (MDMA users, take note !):

5-HTP is sometimes taken by people coming down from MDMA to relieve post-MDMA dysphoria. As 5-HTP is a necessary precursor for the brain to produce more serotonin, and MDMA use depletes a person's natural serotonin levels.

A research conducted by Wang et al. in 2007 suggested a recovery, when MDMA-induced depletions of 5-HT were restored in rats after administering 5-HTP.

[LadyKalma]

I can't tell the difference day by day, but i can tell a lessening in depression when iv'e been taking 5htp consistently for a week at least. I was told that you're supposed to take it for 3 weeks on 1 week off but idk why so I would read more about it if i was going to start skipping weeks. I do skip weeks when i run out of a bottle and pretty much I can tell within 3 days that I need to be taking it, cause it does increase my mood and well being that much. So i dont know that itll put you to sleep but it may promote regular sleeping patterns of non-depressed people.

[traplord69]

Like you said chipper 200mg definitely helped get me to sleep but aside from that I haven't noticed any other benefits.  I've never had depression or anything like that but I read about it and thought what the hay, hoping it would give me some kind of boost.  That's just me though, I'm sure it works for some people

[Chip (OP)]

Thanks guys ... I can't find consistent data on dosage so i tried 300 mg ... here is some copied text from http://nootriment.com/5-htp-dosage/ :

Tryptophan is an essential amino acid, meaning that it cannot be synthesized by the human body and must be acquired from dietary sources. Tryptophan is found in many protein rich foods including red meat, poultry, eggs, milk, edamame, and chickpeas.

5-HTP acts as a metabolic intermediary in the production of Serotonin and Melatonin from Tryptophan. Some people take Tryptophan supplements for mood enhancement and appetite suppression purposes. However, a dosage of 5-HTP instead avoids one of the metabolic steps, and therefore may be more direct.

Using the appropriate 5-HTP dosage may help increase levels of the neurotransmitters Serotonin and Melatonin in the brain.

It is important to note that 5-HTP may be dangerous if taken at exceptionally high doses (over 500mg/day). Always read the supplement label and instructions carefully !

For improving depression symptoms, one research study used 150-300mg of 5-HTP daily in up to three divided doses for 2-6 weeks with mixed evidence of benefit. In another study, 150-400 mg of 5-HTP daily for eight weeks had similar effects in reducing symptoms of depression as 20-40 mg of fluoxetine (Prozac) daily.

For anxiety, some sources recommend a 5-HTP dosage of 50mg each day. Dosage may be increased if advised to do so by a doctor. Some sources recommend taking 50mg capsules three times a day, but a doctor will be able to advise the most appropriate dosage on a case-by-case basis.

5-HTP is sometimes used as a sleep aid because of its connection to Melatonin production. For sleep problems like insomnia, some sources recommend a dose of 100-200mg taken with 8 ounces of water before bedtime.

For headaches and migraines, sources say that on average 300-600mg can be taken daily in divided portions. An amount this high should not be taken on an on-going basis though. Again, these dosages will vary at the discretion of a medical professional.

Clinical studies have shown that 5-HTP may be able to relieve symptoms of fibromyalgia, including pain, morning stiffness, anxiety, and insomnia. For fibromyalgia, some sources recommend a dosage of 5-HTP 100 mg, taken 3-4 times per day.

5-HTP has also been used for weight loss in obese individuals. In a research study, a 5-HTP dosage of 250-300 mg taken three times per day before meals has been seen to improve satiety, decrease caloric intake, and decrease weight in obese women.

I bought 5 grams today so i'll see if it brings any benefits and report back.

[Chip (OP)]

I can't tell the difference day by day, but i can tell a lessening in depression when iv'e been taking 5htp consistently for a week at least. I was told that you're supposed to take it for 3 weeks on 1 week off but idk why so I would read more about it if i was going to start skipping weeks. I do skip weeks when i run out of a bottle and pretty much I can tell within 3 days that I need to be taking it, cause it does increase my mood and well being that much. So i dont know that itll put you to sleep but it may promote regular sleeping patterns of non-depressed people.

@LadyKalma, what is your dosage, please ?

[LadyKalma]

I have been taking 200mg a day at one dosage time, before bed when i take the rest of my vitamins and stuff.

[Roman Totale]

I was just reading up on this supplement, and considering it myself.  L-methylfolate (5-MTHF) is also pretty interesting.

Any updates?  Noticing any effects at the 10-day mark?

[Chip (OP)]

Haven't taken it every night and haven't noticed anything perceptible.

I seem to fall asleep quickly but have frequent (2 or 3) awakenings still.