Fent Hcl + Subs

[demisa (OP)]

I have one of those 10ml spray bottles, it contains 1000ug of fent hcl per ml of liquid.  Each spray is 100ug.  I have been taking 6-8mg of subs a day for almost two years, i want to take a little vacation.   I have read somewhere that fent hcl has a higher binding affinity than bupe, and it will bust right through and it should work.  I guess i have two questions.. has anyone had any experience with this? Also if I used fent, say I dose 3 times and stop at 10pm and go to sleep, when could I take the subs again.. I only have found experiences with people using patches, which stays in your skin for days...

[corlene]

Fent has a very short half life, 8 to 12 hours is enough

[Opus]

paging rj..

[demisa (OP)]

Well I took 4 squirts, and I actually feel a little bit of mood lift, energy and a slight buzz.  So it does work to some degree.

[robojunkie]

If you are dosing several times a day at 0.1 mg per "puff" and you do three or four at a time, I'll assume your tolerance is still low and you are cutting through the subs.  As long as you have not completely come off them while doing the fent you should be fine just taking a smaller dose and working it up after 18 hours.  If you go sooner than that and I'm reading between the lines here assuming you have an ample supply you needn't worry about precipitated withdrawal as fent will cut through bupe fairly easily despite the fact that bupe's pKi is way higher (binding/dissociation constant).  I could shoot 5 mgs of fent right through 8 mg x 2/day of bupe easily.  If however you do not have extended supply and have come off the bupe I would wait at least 18-24 hours if you have normal tolerance and if you have one of the epic type tolerances which I assume you do not based on the numbers you gave no bupe is gonna cover the withdrawal and expect precipitated WDs no matter what unless you've already maxed out the sickness and its plateaued but I doubt this is the case as you would already be doing way more.

[demisa (OP)]

I have not come off the bupe, I just added 12 squirts of fent to my night last night between 8pm and 12am.  Went to sleep around 1am but did not redose.  Its 11am now, I feel totally normal, I am guessing that a lot of my receptors are still filled with bupe since I have been on it for 2 yrs, and that the fent was probably not as strong as advertised.  I took 1mg of bupe just now, its been 15 minutes and i feel fine... wierd

[demisa (OP)]

Just an update for those maybe doing something like this in the future, I took another 2mg of subs about 1 hour after taking the test 1mg dose.  I caught a pretty strong mood lift from it.  I rarely get those anymore, every once in awhile I'll feel "pleasant" an hour after taking a sub dose.  So this worked out really well, I got decently high for 4 hours last night, then woke up feeling fine, and went back on my subs 12 hrs after my last fent dose.   I am assuming if I did this quite often it would not work that way, but its nice to know I can have a fun saturday night once and awhile..  I am on the boarder line of getting off subs and going back to using kratom/seed tea for maintenance and getting dope when I can afford it, but I know what the end result of that will be... 

[Edhorfin]

I take about .5mg subutex per day, and am sometimes prescribed Dilaudid for kidney stones. I can feel the Dilaudid almost as if I was opiate naive 24 hours after my last sub dose.

With the binding affinity of Fentanyl, you should feel it just fine. I also feel the "early subutex glow" the first dose after using a full agonist.

[Opus]

I take about .5mg subutex per day, and am sometimes prescribed Dilaudid for kidney stones. I can feel the Dilaudid almost as if I was opiate naive 24 hours after my last sub dose..

This is *highly* subjective. I can punch through 4mg bup within about 4-6 hours after dosing. I don't start to get any real "blocking" until at least 6mg; but this is widely variable, some people can be fully blocked for a full day+ by 4mg.