Amino Acids with Psychoactive Synergy (Generated by AI)

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🧬 Amino Acids with Psychoactive Synergy

This list includes amino acids known to influence neurotransmitter systems or support the action, metabolism, or recovery phases of major psychoactive drugs. For informational purposes only.

🌟 L-Tyrosine
💊 Synergy: Phenethylamines, Amphetamines, Dopamine Agonists 
🧠 Function: Precursor to dopamine, norepinephrine, and epinephrine 
⚠️ May enhance stimulant response or recovery from stimulant depletion

🌈 DL-Phenylalanine (DLPA)
💊 Synergy: Stimulants, Opiates 
🧠 Function: D-isomer inhibits enkephalinase (preserves endorphins), L-isomer is a dopamine precursor 
🛡️ May reduce pain and improve mood during stimulant or opiate withdrawal

🌀 L-Tryptophan
💊 Synergy: SSRIs, Empathogens, Tryptamines 
🧠 Function: Precursor to serotonin 
🌙 Supports sleep and mood regulation; do NOT mix with serotonergic drugs unsupervised

☯️ 5-HTP (5-Hydroxytryptophan)
💊 Synergy: MDMA, SSRIs, Psilocybin (Post-use Recovery) 
🧠 Function: Immediate precursor to serotonin 
🚨 Caution: Risk of serotonin syndrome with active serotonergic substances

⚡ L-Theanine
💊 Synergy: Stimulants, Psychedelics, Caffeine 
🧠 Function: Promotes calm focus via GABA and glutamate modulation 
🧘‍♂️ Smooths stimulant experience, reduces anxiety

💤 L-Glycine
💊 Synergy: NMDA Antagonists (Ketamine, DXM), GABAergics 
🧠 Function: Co-agonist at NMDA receptors; calming effects 
🌌 May enhance dream vividness, promote sleep

🧊 L-Glutamine
💊 Synergy: Dissociatives, Nootropics, Stimulants 
🧠 Function: Precursor to glutamate and GABA 
🔄 Supports CNS recovery after overstimulation

💪 L-Arginine
💊 Synergy: Psychedelics, Nootropics, MDMA 
🧠 Function: Boosts nitric oxide, enhances circulation 
❤️ May increase intensity of experience and body load

🔥 L-Citrulline
💊 Synergy: Phenethylamines, Sexual Enhancers 
🧠 Function: Converts to Arginine, increases NO 
🫀 Vasodilation may enhance physical rush or tactile pleasure

🛡️ L-Cysteine (NAC precursor)
💊 Synergy: Stimulants, Alcohol, MDMA 
🧠 Function: Antioxidant, glutathione precursor 
🧬 Protects against neurotoxicity and oxidative stress

⚙️ Acetyl-L-Carnitine (ALCAR)
💊 Synergy: Stimulants, Cognitive Enhancers 
🧠 Function: Enhances mitochondrial function and acetylcholine metabolism 
🔋 Boosts energy, reduces mental fatigue

🎯 Taurine
💊 Synergy: Stimulants, Alcohol, Benzodiazepines 
🧠 Function: GABAergic modulator 
🧘‍♀️ May blunt overstimulation and improve hydration

🧠 L-Histidine
💊 Synergy: MAO inhibitors, Dream Inducers 
🧠 Function: Histamine precursor, supports wakefulness and immune balance 
😵‍💫 High doses may cause vertigo or nausea in sensitive individuals

🌿 Beta-Alanine
💊 Synergy: Phenethylamines, Performance Drugs 
💥 Buffers lactic acid, may increase endurance or paresthesia 
⚠️ May intensify body tingles when mixed with stimulants

📜 Notes

• ⚠️ Combining any supplement with psychoactive drugs carries risk—do your own research.
• 🧪 These pairings are often based on anecdotal, nutritional, or experimental neuroscience data.
• 🔍 Many of these amino acids also aid post-experience recovery or protect neurotransmitter systems.

Compiled by ChatGPT | Public Domain | For educational use only