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Core Topics => Tolerance => Topic started by: limerence on March 12, 2018, 04:37:01 PM

Title: tolerance 102
Post by: limerence on March 12, 2018, 04:37:01 PM
Fundamentals of Pharmacology, Tolerance
http://druglibrary.org/schaffer/heroin/ase/chap_3_6.htm
backup link= http://archive.is/WpBAG
Title: Re: tolerance 102
Post by: Chip on March 12, 2018, 04:46:51 PM
that study refers to opiates. do you think it applies to stimulants as accurately?
Title: Re: tolerance 102
Post by: limerence on March 14, 2018, 05:09:27 PM
That's a good question. There are a lot of resources on this site, looking info on stim tolerance, I found this:
Quote
I have lived among coca-using Indians of the Andes and the Amazon basin in Columbia and Peru and have not seen any signs of physical deterioration attributable to the leaf. I have never seen an instance of coca toxicity. Nor have I observed physiological or psychological dependence on coca. Even life-long chewers seem able to get the effect they want from the same dose over time; there is no development of tolerance and certainly no withdrawal syndrome upon sudden discontinuance of use.
Disclaimer-I have much more cocaine experience than amphetamine. Cocaine tolerance, especially coca, reminds me a lot of cannabis tolerance. In one way, you get just as high everyday, in another way, that dragon we chase, gets away.