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21
Dissociatives / Ketamine’s antidepressive effects tied to opioid system in brain
« Last post by Chip on February 04, 2024, 04:40:39 PM »
Ketamine and opioids are best taken independently and staggered. This is gleaned from personal experience and the belowmentioned:

https://med.stanford.edu/news/all-news/2018/08/ketamines-antidepressive-effects-tied-to-opioid-system-in-brain.html
22
https://www.predatornutrition.com/articlesdetail?cid=9-mbc-nootropic-review

an excerpt:

Using 9-Me-BC To Reduce Stimulant Tolerance


As we have touched on, 9-MBC can help regenerate dead dopaminergic neurons. With this in mind, it has promise for playing a part in recovery of the dopaminergic system, which may be necessary following abuse of stimulants such as caffeine.

Many athletes will use periods such as deloads to cut out caffeine when the performance benefit is no longer needed, in the hopes that it will help them resensitise to pre-workout type products. In theory, this may be a great window to use 9-MBC!

Anecdotally, users have reported better results compared to using substances including BPC-157 and Bromantane for the same purpose.
24
Nootropics / Phenylpiracetam Interesting Facts
« Last post by Chip on February 04, 2024, 06:12:36 AM »
Phenylpiracetam

source: https://en.m.wikipedia.org/wiki/Phenylpiracetam

An excerpt:

Rats administered 100 mg/kg phenylpiracetam performed, on average, 375% more work than rats given placebo, and consumed little non-preferred rat chow. In comparison, rats administered 1mg/kg d-amphetamine or 10 mg/kg methylphenidate performed, on average, 150% and 170% more work respectively, and consumed half as much non-preferred rat chow.

25
Dissociatives / A Systematic Review of the Implications of Recreational Nitrous Oxide Use
« Last post by Chip on February 04, 2024, 05:37:46 AM »
A Systematic Review of Recreational Nitrous Oxide Use: Implications for Policy, Service Delivery and Individuals

Abstract

Background: Nitrous oxide (N2O) is a dissociative anaesthetic that is sometimes used recreationally. The prevalence of N2O use is difficult to quantify but appears to be increasing. Research on N2O harms and application of harm reduction strategies are limited. The aim of this mixed method systematic review was to collate and synthesise the disparate body of research on recreational nitrous oxide use to inform harm reduction approaches tailored for young people.

https://pubmed.ncbi.nlm.nih.gov/36141850/&ved=2ahUKEwjv0pflj5CEAxWCVWwGHeoFC7QQFnoECCcQAQ&usg=AOvVaw1ZTGqn16m2xE81gQW-vAf7
26
Phenethylamines / Restoring Dopamine with 9-ME-BC: Optimal Dosing/Protocols
« Last post by Chip on February 04, 2024, 05:28:44 AM »
27
Phenethylamines / Re: The many health benefits of Meth in low, pharmaceutical-grade doses
« Last post by Chip on February 04, 2024, 04:25:27 AM »
Protective Effect of Low Dose of Methamphetamine on The Amount of Extracellular Glutamine in Primary Fetal Human Astrocytes Induced by Amyloid Beta

https://pubmed.ncbi.nlm.nih.gov/35451579/
28
Hallucinogens/Psychedelics / Bufo alvarius: the PSYCHEDELIC TOAD of the Sonoran Desert
« Last post by Chip on February 03, 2024, 04:41:45 AM »
Sustainable tripping

OMG - FROG forums

https://www.frogforum.net/showthread.php/642-Bufo-alvarius

Here is the Sonoran Bufo alvarus

Attachments: bufo.pdf

29
Dissociatives / Re: Ketamine Bladder Damage – What You Need to Know
« Last post by Chip on February 02, 2024, 07:57:24 PM »
*bump*
Pages: 123456 ... 10

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