dopetalk does not endorse any advertised product nor does it accept any liability for it's use or misuse

This website has run out of funding so feel free to contribute if you can afford it (see footer)

« previous next »
Pages: 1   Go Down

Author Topic: GABA subunits A (there are 5) and B (there are 2) differences and drug examples  (Read 1075 times)

Offline Chip (OP)

  • Server Admin
  • Hero Member
  • *****
  • Administrator
  • *****
  • Join Date: Dec 2014
  • Location: Australia
  • Posts: 6651
  • Reputation Power: 0
  • Chip has hidden their reputation power
  • Gender: Male
  • Last Login:April 25, 2024, 08:06:39 PM
  • Deeply Confused Learner
  • Profession: IT Engineer
GABA subunits A (there are 5) and B (there are 2) differences and drug examples
« on: February 08, 2024, 10:09:01 AM »
GABA type A (GABAA) receptor is a ligand-gated chloride channel which mediates fast inhibitory signals through rapid postsynaptic membrane hyperpolarization whereas the metabotropic GABAB receptor produces slow and prolonged inhibitory signals via G proteins and second messengers (GPCRs).

As far as drugs go, Diazepam and Alprazolam are examples of agonists that bind to GABA A and do so quickly whilst Gabapentinoids like Baclofen or Phenibut bind to GABA B and may take hours to kick in yet GHB is also an agonist there but kicks in must faster.

« Last Edit: February 08, 2024, 12:28:55 PM by Chip »
friendly
0
funny
0
informative
0
agree
0
disagree
0
like
0
dislike
0
No reactions
No reactions
No reactions
No reactions
No reactions
No reactions
No reactions
Our Discord Server invitation link is https://discord.gg/jB2qmRrxyD
Pages: 1   Go Up
« previous next »
Tags:
 

Related Topics

  Subject / Started by Replies Last post
9 Replies
10457 Views 		Last post November 30, 2019, 06:00:55 AM
by Chip
4 Replies
10483 Views 		Last post December 19, 2016, 07:24:07 AM
by milky
0 Replies
5474 Views 		Last post August 09, 2017, 06:51:10 AM
by Chip
3 Replies
6581 Views 		Last post September 02, 2017, 10:06:18 AM
by Chip
0 Replies
4287 Views 		Last post May 14, 2018, 09:35:43 PM
by Chip
0 Replies
2120 Views 		Last post June 25, 2018, 04:13:41 AM
by Chip
0 Replies
4131 Views 		Last post December 30, 2018, 10:03:59 PM
by Chip
0 Replies
3460 Views 		Last post May 27, 2019, 06:44:19 PM
by Chip
0 Replies
3832 Views 		Last post September 04, 2019, 12:48:37 AM
by Chip
0 Replies
2496 Views 		Last post June 25, 2021, 11:35:19 AM
by Chip


dopetalk does not endorse any advertised product nor does it accept any liability for it's use or misuse




TERMS AND CONDITIONS

In no event will d&u or any person involved in creating, producing, or distributing site information be liable for any direct, indirect, incidental, punitive, special or consequential damages arising out of the use of or inability to use d&u. You agree to indemnify and hold harmless d&u, its domain founders, sponsors, maintainers, server administrators, volunteers and contributors from and against all liability, claims, damages, costs and expenses, including legal fees, that arise directly or indirectly from the use of any part of the d&u site.

TO USE THIS WEBSITE YOU MUST AGREE TO THE TERMS AND CONDITIONS ABOVE

Founded December 2014
SimplePortal 2.3.6 © 2008-2014, SimplePortal