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Core Topics => Drugs => GABAergics => Topic started by: Jega on October 05, 2015, 07:02:03 PM

Title: Benzos are Water Solubility
Post by: Jega on October 05, 2015, 07:02:03 PM
Note: Someone of these are only available in europe.

I created this thread so you all know benzodiazepines are hardly absolvable for dissolve for injection in water. You know--Harm Reduction

There is also a TON of information on these sites (sorry no RC's) so if your interested in benzos there is plenty of reading to do.

Alprazolam (Xanax) - 0.04 mg/mL http://www.drugbank.ca/drugs/DB00404

Chlordiazepoxide (Librium) - 2 mg/mL http://www.drugbank.ca/drugs/DB00475

Clonazepam (Klonopin) - < 0.1 mg/mL http://drugbank.ca/drugs/DB01068

Cloxazolam (Cloxazolazepam) 0.0266 mg/mL http://www.drugbank.ca/drugs/DB01553

Diazepam (Valium) - 0.05 mg/mL http://drugbank.ca/drugs/DB00829

Estazolam (ProSom) - 0.0015 mg/mL http://drugbank.ca/drugs/DB01215

Flurazepam (Dalmane) - 500 mg/mL http://drugbank.ca/drugs/DB00690

Halazepam (Halazepam) 0.0017 mg/mL http://www.drugbank.ca/drugs/DB00801

Ketazolam (Ketazolam) 0.0839 mg/mL http://www.drugbank.ca/drugs/DB01587

Lorazepam (Ativan) - 0.08 mg/mL http://drugbank.ca/drugs/DB00186

Midazolam (Dormicum) - 0.024 mg/mL http://www.drugbank.ca/drugs/DB00683

Oxazepam (Serax) - 0.179 mg/mL http://drugbank.ca/drugs/DB00842

Temazepam (Restoril) - 0.164 mg/mL http://drugbank.ca/drugs/DB00231

Triazolam (Halcion) - 0.00453 mg/mL http://drugbank.ca/drugs/DB00897
Title: Re: Benzos are Water Solubility
Post by: Zoops on October 06, 2015, 01:35:00 AM
So if you want to shoot your benzos, shoot flurazepam (Dalmane). I tried it once. Was like >meh<.
Title: Re: Benzos are Water Solubility
Post by: Chip on October 06, 2015, 01:48:47 AM
and some anti-psychs. are too ... so i shot a bunch out of curiosity. wiki the drug for solubility data.

but don't bother, as we all know, they never feel groovy anyway (unless you should find yourself over~amped and even then, take them as scribed.
Title: Re: Benzos are Water Solubility
Post by: theSWPK on October 06, 2015, 01:53:47 AM
When my was helping his wife's family clean out their attic, he came across diazepam for injection (IV/IM). I don't remember the details of the solution but it was pretty cool shit, burned like hell though, so I'm assuming it was in some kind of alcohol.

I would mix shots of oxymorphone with half diazepam half water. Never so much to endanger myself with a risk of overdosing and never alone. Good combo. That sudden heavy sedation was groovy.
Title: Re: Benzos are Water Solubility
Post by: Chip on October 06, 2015, 02:08:49 AM
man, talk about Diaz. amps ... they came my way for a while and i just added some stims into the mix, just for good measure.

i don't think it's wise to shoot too much of it as it's mainly for infusions, i think ...
Title: Re: Benzos are Water Solubility
Post by: Snoop on October 06, 2015, 02:43:50 AM
Ive known lots of not so brights in my lifetime that would IV their Alprazolam etc.

...... And swore by it.

(massages temples)

Ive an in with a triage nurse I know... Amps of Ativan and Valium when the getting is good.

Nothing like pharmaceutical grade benzos straight to the dome piece.

Title: Re: Benzos are Water Solubility
Post by: Jega on October 06, 2015, 04:52:36 AM
Propylene Glycol are what is used in Diazepam and Lorazepam (not sure about Midazolam but i'd put money on it) since they are all soluble in Propylene Glycol. That's also why they are so oily/tick coming out.

man, talk about Diaz. amps ... they came my way for a while and i just added some stims into the mix, just for good measure.

i don't think it's wise to shoot too much of it as it's mainly for infusions, i think ...

And one or two shot of a benzo is a tier 1 medications for a panic attack or a seizure.
Title: Re: Benzos are Water Solubility
Post by: Opus on October 06, 2015, 05:55:55 AM
Many things soluble in PG are also soluble in PEG (Polyethylene Glycol), which can be found in decent amounts in some eye drops.

Title: Re: Benzos are Water Solubility
Post by: Jega on October 06, 2015, 06:01:57 AM
Many things soluble in PG are also soluble in PEG (Polyethylene Glycol), which can be found in decent amounts in some eye drops.
Rhoto uses Naphazoline but my question is are the only ingredients in Polyethylene Glycol be harmful or is there anything to watch out for?
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