In Animal Studies, Ketamine Reverses Brain Changes Linked With Acute Drug Withdr

[Chip (OP)]

I suggested using a little Ketamine to a friend and we'll see how it goes with respect to Methamphetamine withdrawal and use.

See https://www.bbrfoundation.org/content/animal-studies-ketamine-reverses-brain-changes-linked-acute-drug-withdrawal

An excerpt:

Administering ketamine to animals during amphetamine withdrawal did restore normal signaling of dopamine neurons. However, the signs of despair in the animals did not diminish. According to the scientists, this suggests that the neural processes giving rise to negative emotions experienced during withdrawal are different than those that underlie depression.

The scientists theorize that by reversing changes to dopamine signaling during acute withdrawal, treatment with ketamine could help reduce the risk of further drug use.