Central nervous system | Hallucinations, esp. tactile | Psychotic symptoms |
| Dyskinesia | Cerebrovascular disease/stroke |
| Seizures | Movement disorders, e.g., dystonic reactions, akathisia, choreoathetosis, tardive dyskinesia |
Cardiovascular system | Tachycardia | Myocarditis |
| Hypertension | Cardiomyopathy |
| Myocardial infarction | Myocardial fibrosis |
| Arrhythmias | Myocardial infarction |
Pulmonary | Cough, shortness of breath, wheezing | Interstitial pneumonitis |
| Pulmonary edema, hemorrhage | Bronchiolitis obliterans |
| Pneumothorax | |
Renal | | Renal ischemia |
| | Renal failure |
Gastrointestinal | Reduced gastric motility | Gastric ulceration and perforation |
| | Intestinal infarction |
| | Ischemic colitis |
Liver | | Viral hepatitis secondary to contaminated syringe use |
Endocrine | Reduced prolactin | Inc, normal or dec. prolactin |
| Increased epinephrine, CRH, ACTH, cortisol and luteinizing hormones | Normal testosterone, cortisol, LH, thyroid hormones |
Musculoskeletal | Movement disorders (see CNS) | Rhabdomyolysis |
Head and neck | Rhinitis | Rhinitis |
| | Perforated nasal septum |
| | Nasal and gingival ulceration |
| | Sinusitis |
| | Dental decay and periodontal disease |
| | Xerostomia |
| | Corneal ulcers |
Immune system | | Vasculitis sysndromes |
Sexual function | | Erectile dysfunction |
| | Irregular menses |
Reproductive | Vaginal bleeding | FDA category C |
| Abruption placenta | Placenta previa |
| Premature rupture of membranes | Low birth weight |
General/other | Dehydration | Weight loss |
| | Nutritional deficits |