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Author Topic: RNA Molecule Rejuvenates Ageing Mice by Restoring Old Cells  (Read 1287 times)

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RNA Molecule Rejuvenates Ageing Mice by Restoring Old Cells
« on: January 21, 2025, 05:40:13 AM »
Source: https://www.nature.com/articles/d41586-025-00032-3

See also: An article about "Ageing studies in five animals suggest how to reverse decline" at https://www.nature.com/articles/d41586-023-01040-x

17 January 2025

A microRNA molecule rejuvenates ageing mice by restoring the old cells.

Mice injected with the microRNA molecule, lived longer and had fewer markers of ageing when treated with a molecule called miR-302b.

They regrew lost hair and maintained brain health, however it’s not yet known if the treatment would work in people[/b].

Injecting old mice with an RNA molecule seems to reverse some signs of ageing — helping them to live longer, regrow hair and maintain their physical and mental abilities.

sorry ... so see the source links for recursive links (not shown here) and search on the title directly to see free versions of the study, as they are *usually* freely available
.

The treatment, described in Cell Metabolism on 15 January, 2025 -- works by targeting one of the key hallmarks of the ageing process: a stage called cellular senescence, in which cells lose their ability to replicate. Researchers hope the findings could one day lead to the development of anti-ageing drugs, but more work is needed to determine whether they translate to people.

As people age, more of their cells become senescent and release chemicals called cytokines, which can trigger inflammation. This reduces the body’s ability to withstand illness and to heal, and has been linked to conditions including cancer, cardiovascular disease, diabetes and declines in cognitive function.

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