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Core Topics => Harm Reduction => Topic started by: candy on June 24, 2016, 09:10:01 PM

Title: Drug Combinations and Safety
Post by: candy on June 24, 2016, 09:10:01 PM
http://wiki.tripsit.me/images/3/3a/Combo_2.png (http://wiki.tripsit.me/images/3/3a/Combo_2.png)

I found this today and think it could be a very helpful tool when combining different substances.
Some of you may have already had a look at the link on other sites.

I think it is handy to have around when questioning the safety of any drugs we may combine.
In fact, our safety is very important.
Title: Re: Drug Combinations and Safety
Post by: Zoops on June 24, 2016, 09:54:02 PM
Can you explain how to use this chart. It looks interesting. But what do the "up" and "down" arrows mean. Obviously, an "X" means "don't do it," but beyond that I can't figure it out.

I noticed that the chart doesn't appear to have a combination of SSRIs and tramadol addressed. This is an absolute NO-GO combination. NEVER combine tramadol with an SSRI, especially sertraline (Zoloft). This can and will cause seizures. I know because it's happened to me - twice.
Title: Re: Drug Combinations and Safety
Post by: Dog Food on June 25, 2016, 02:35:29 AM
http://wiki.tripsit.me/images/3/3a/Combo_2.png

The first link had two seperate halves of the chart for printing i think. i clicked this link on the bottom and got the whole chart in one.

And yes, you are correct, the ssri and tramadol combo is a red one. Theres a guide to tell you which order the squares go in from best to worst(on the full one)
Title: Re: Drug Combinations and Safety
Post by: Zoops on June 25, 2016, 04:04:39 AM
Thanks for posting that full version of the chart with the legend for interpreting it. Interesting that cannabis and LSD is a "caution" combination. That was practically my food for life in college.

Another fun one that is a "caution" is LSD and amphetamines. One of the best trips I had was sniffing Ritalin while on LSD and diazepam.
Title: Re: Drug Combinations and Safety
Post by: thetalkingasshole on June 25, 2016, 10:12:14 AM
Thanks for posting that full version of the chart with the legend for interpreting it. Interesting that cannabis and LSD is a "caution" combination. That was practically my food for life in college.

Another fun one that is a "caution" is LSD and amphetamines. One of the best trips I had was sniffing Ritalin while on LSD and diazepam.

MDMA+LSD is pretty wonderful, especially if you take the mdma about an hour after the L

Amphetamine+LSD is a pretty fucked up trip IME


i knew a few hippy/heads who loved to do cocaine on LSD
of course none of them are alive still

RESPECT THE L!
Title: Re: Drug Combinations and Safety
Post by: candy on June 25, 2016, 12:16:46 PM
@Dog Food, Thank you for posting the other link. I modified and updated my op.

That is scary Zoops. That is information that needs to be given to patients by their doctors and by pharmacists. Both those medications are given out by script and most certainly given together quite often.
Even the information they send you home with from the pharmacy doesn't always include drug interactions and what they do give you is such small print I can only read it with a magnifying glass.
Title: Re: Drug Combinations and Safety
Post by: Zoops on June 27, 2016, 03:07:27 PM
@Dog Food, Thank you for posting the other link. I modified and updated my op.

That is scary Zoops. That is information that needs to be given to patients by their doctors and by pharmacists. Both those medications are given out by script and most certainly given together quite often.
Even the information they send you home with from the pharmacy doesn't always include drug interactions and what they do give you is such small print I can only read it with a magnifying glass.

Tramadol and sertraline is a hugely bad seizure-inducing combination. When I had my seizures from that combo, I was taking 300mg of tramadol on top of my 100mg/d of sertraline. But in the elderly or anyone with a reduced seizure threshhold, it's dangerous to take like 100mg tramadol on top of their daily sertraline dose. Oftentimes, tramadol and an SSRI would be prescribed by different specialists and the patient probably won't tell them about the meds they're on.

A shrink might prescribe the SSRI and a GP, orthopedist or pain specialist might prescribe tramadol.
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