An interdisciplinary overview of α-PVP -- one of the "pyrros"

[Chip (OP)]

source: https://www.sciencedirect.com/science/article/abs/pii/S1878652922000700

I was researching Cathinones as they're popular in Europe as Research Chemicals and this was brought to my attention as it's also a "pyrro" or α-Pyrrolidinohexanophenone.

It was described to me as far more addictive than Methamphetamine and I wanted to know more so here are some excerpts. See the source link above for the full paper.

December 2022

Summary

α-PVP has become one of the most dangerous drugs today. α-PVP is chemically the ketone analog of proline.

Physically, it is an odorless, colorless solid crystal form. α-PVP is also chemically called α-pyrrolidinovalerophenone, 1-Phenyl-2- (pyrrolidine-1-yl) pentane-1-one, α-Pyrrolidinopentiophenone.

In this study, we focused on a general review of this drug, α-PVP, which has become very popular among young people.

The study mainly focused on the chemical (synthesis, analogs) and physicochemical (such as density, viscosity, polarity, surface tension) properties, pharmacodynamics, pharmacokinetics, and toxic effects of α-PVP, as well as psychological effects and preventive studies.

α-PVP users often appear to cause loss of consciousness, difficulty breathing, and, worst cases, death. It has high toxicity. It has been understood that such a synthetic chemical can be produced in high amounts in a laboratory environment and chemically.

The information in the literature on these issues is generally collected in this overview article. In the conclusion part of the study, the negative effects of α-PVP were mentioned, and suggestions were made.

Conclusion

In this study, the drug α-PVP, which is one of the biggest problems of the last few days, was examined. In the study, firstly, the chemical properties of α-PVP were examined.

The fact that it is soluble in water and almost in many organic solvents paves the way for using α-PVP by other means. Since α-PVP is a potent stimulant, its abuse can cause severe and life-threatening adverse effects in humans. α-PVP users often appear to cause loss of consciousness, difficulty breathing, and, worst ...