Author Topic: Have scientists found a drug to stop Alzheimer's disease?  (Read 967 times)

Offline Chip (OP)

  • Server Admin
  • Hero Member
  • *****
  • Administrator
  • *****
  • Join Date: Dec 2014
  • Location: Australia
  • Posts: 5333
  • Reputation Power: 0
  • Chip has hidden their reputation power
  • Gender: Male
  • Last Login:Today at 12:47:10 PM
  • Deeply Confused Learner
Have scientists found a drug to stop Alzheimer's disease?
« on: July 20, 2015, 04:55:37 PM »
http://www.telegraph.co.uk/news/science/science-news/11749641/Have-scientists-found-a-drug-to-stop-Alzheimers-disease.html

Have scientists found a drug to stop Alzheimer's disease?

Eli Lilly is due to announce results of its latest trial into Solanezumab at the Alzheimer's Association International Conference on Wednesday.

The first drug that can halt the progression of Alzheimer’s disease if caught early is expected to be unveiled this week.

Trials have been ongoing into a new treatment called Solanezumab which appears to stop the degenerative disease in its tracks.

The results will be announced by drugs giant Eli Lilly on at the Alzheimer’s Association International Conference on Wednesday morning but if positive it will be the first drug proven to be effective for treating dementia.

Solanezumab, is an antibody which works by binding to the amyloid plaques which cause Alzheimer’s disease and clearing them from the brain.

Initial trials failed to show any benefit, but when researchers went back over the data they found that it seemed to work in people with mild symptoms and launched a new study.

There are 850,000 people currently suffering from dementia in the UK, with Alzheimer's disease being the most common type. The disease kills at least 60,000 people each year.

Eric Karran, director of research at Alzheimer's Research UK, said it would be interesting to find out if the treatment worked in the long term.

"Current treatments only help with symptoms. They enable nerve cells to communicate with each other more effectively, but don't stop the underlying disease from getting worse," he said.

"Eventually the effect of these treatments wears off as the damage to the brain overwhelms the modest benefit afforded by the drugs."
Officially, Eli Lilly is saying nothing about its results.

However, its researchers presented results at a recent conference where they said: "Results from 28 weeks' treatment suggest patients who received Solanezumab had a cognitive benefit not recovered by patients who began Solanezumab later."

In a final sentence, they added: "This is thought consistent with a treatment effect that changes the underlying pathology of Alzheimer's disease."

Many organisations are currently trying to find a cure for Alzheimer’s disease.

Last year Stanford University announced that it had discovered that boosting the immune system could help the body to clear away the toxic plaques on its own. They are currently developing a drug which can boost the protein needed to trigger the ramped up immune response in the brain.

Imperial College has discovered how to turn off an enzyme which is driving many incurable diseases including Alzheimer’s and cancer. Scientists at Ulster and Lancaster Universities found that diabetes drugs Liraglutide and Lixisenatide prevent amyloid plaques forming in mice.

And a number of organisations now claim to have developed tests which can pick up the earliest signs of dementia 10 years before the first symptoms appear.

But if Eli Lilly reports a success on Wedsneday it will be the first phase three trial in patients to show beneficial results and will mark a breakthrough in the treatment of Alzheimer's.
« Last Edit: July 20, 2015, 07:36:12 PM by smfadmin »
Over 90% of all computer problems can be traced back to the interface between the keyboard and the chair !

Tags:
 

Related Topics

  Subject / Started by Replies Last post
3 Replies
1149 Views
Last post January 26, 2016, 07:12:05 AM
by candy
0 Replies
724 Views
Last post February 16, 2016, 09:13:15 AM
by Chip
0 Replies
883 Views
Last post May 24, 2016, 01:37:58 PM
by Chip
0 Replies
880 Views
Last post July 13, 2016, 09:59:37 AM
by Chip
1 Replies
799 Views
Last post November 16, 2016, 08:46:57 AM
by MoeMentim
4 Replies
920 Views
Last post February 03, 2018, 05:20:29 PM
by DreamerOnTheRun
0 Replies
387 Views
Last post February 14, 2018, 07:37:02 PM
by Chip
0 Replies
307 Views
Last post February 16, 2018, 10:36:23 PM
by Chip
0 Replies
139 Views
Last post May 02, 2018, 03:38:53 PM
by Chip
3 Replies
296 Views
Last post June 21, 2018, 09:31:06 PM
by bonedust




TERMS AND CONDITIONS

In no event will d&u or any person involved in creating, producing, or distributing site information be liable for any direct, indirect, incidental, punitive, special or consequential damages arising out of the use of or inability to use d&u. You agree to indemnify and hold harmless d&u, its domain founders, sponsors, maintainers, server administrators, volunteers and contributors from and against all liability, claims, damages, costs and expenses, including legal fees, that arise directly or indirectly from the use of any part of the d&u site.


TO USE THIS WEBSITE YOU MUST AGREE TO THE TERMS AND CONDITIONS ABOVE



Founded December 2014