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Author Topic: Pregabalin: Its Pharmacology and Use in Pain / Burns Management  (Read 1269 times)

Offline Chip (OP)

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Pregabalin: Its Pharmacology and Use in Pain / Burns Management
« on: September 11, 2017, 08:51:47 PM »
I will ask for this to treat my chemical burn because it hurts a lot ... I need a non-opioid drug if possible.

Pregabalin in severe burn injury pain: a double-blind, randomised placebo-controlled trial:

https://www.ncbi.nlm.nih.gov/pubmed/21398038

here is it's analgesic value:

source: http://journals.lww.com/anesthesia-analgesia/Fulltext/2007/12000/Pregabalin__Its_Pharmacology_and_Use_in_Pain.47.aspx

abstract:

Pregabalin is a new synthetic molecule and a structural derivative of the inhibitory neurotransmitter γ-aminobutyric acid. It is an α2-δ (α2-δ) ligand that has analgesic, anticonvulsant, anxiolytic, and sleep-modulating activities. Pregabalin binds potently to the α2-δ subunit of calcium channels, resulting in a reduction in the release of several neurotransmitters, including glutamate, noradrenaline, serotonin, dopamine, and substance P. In this review, I will discuss the pharmacology of pregabalin and available efficacy studies in pain management. This review will focus on the advances in pregabalin pharmacology since my previous review in 2005.
I do not condone or support any illegal activities. All information is for theoretical discussion and wonder.
All activities discussed are considered fictional and hypothetical. Information of all discussion has been derived from online research and in the spirit of personal Freedom.

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