Companion document to the audio reading. Source: Psychiatrist.com "Author Insight", published October 15, 2026, and the "Sunday Rounds" newsletter of October 18, 2026.
Featuring: Justine Perino, of Nice University Hospital and Université Côte d'Azur
What happens in the first weeks after discharge may matter more than the full year that follows.
Current cannabis use at admission was linked to a 2.8-fold increased risk of psychiatric rehospitalization in the first month after discharge. The association stayed significant through the first three months, but was no longer significant after six months or over the full year.
"The main finding was that current cannabis use was associated with 2.8 fold increased risk of psychiatric rehospitalization during the first month after discharge."
Justine Perino discusses a historical cohort study assessing whether cannabis use at admission is associated with psychiatric rehospitalization after discharge in young adults with bipolar or psychotic disorders. The video focuses on the timing of readmission risk and the first three months after discharge.
In this video overview, Justine Perino, MD, of Nice University Hospital and Université Côte d'Azur, describes an article on cannabis use and time to psychiatric rehospitalization in young adults with bipolar or psychotic disorders. She frames the work as arising from a clinical question: whether cannabis use could be associated with an increased risk of psychiatric rehospitalization after discharge, and whether this risk could change over time.
Perino describes a historical cohort of 200 young adults aged 18 to 29 who were hospitalized for bipolar or psychotic disorders in 2017, with up to five years of follow-up. Information was collected from medical records, including psychiatric history, substance use, and subsequent hospitalizations. She says the analysis used survival analysis and Cox regression models to investigate the association between cannabis use at admission and the timing of psychiatric readmission after discharge.
She reports that cannabis was by far the most commonly used drug in the cohort, with 43% of patients reporting current use, and two-thirds of those reporting daily use. The main finding was that current cannabis use was associated with a 2.8-fold increased risk of psychiatric rehospitalization during the first month after discharge, with the association remaining significant over the first three months but no longer significant after six months or over the full year. Perino also notes limitations, including the retrospective and single-center design, small sample size, and some missing data, and says cannabis use at admission may nevertheless be a marker of a more severe disease course in this population.
| Item | Detail |
|---|---|
| Design | Historical (retrospective) cohort, single center |
| Participants | 200 young adults, aged 18 to 29 |
| Conditions | Bipolar or psychotic disorders |
| Index hospitalization | 2017 |
| Follow-up | Up to 5 years |
| Data source | Medical records (psychiatric history, substance use, subsequent hospitalizations) |
| Analysis | Survival analysis and Cox regression models |
| Exposure | Current cannabis use at admission |
| Outcome | Time to psychiatric rehospitalization after discharge |
| Cannabis use in cohort | 43% current use; two-thirds of those daily |
| Main result | 2.8-fold increased risk of rehospitalization in the first month after discharge |
| Time pattern | Significant through 3 months; not significant at 6 months or over the full year |
| Limitations | Retrospective, single center, small sample, some missing data |
Impact of Cannabis Use on Time to Psychiatric Rehospitalization in Young Adults With Bipolar and Psychotic Disorders: A Survival Analysis J Clin Psychiatry 2026;87(4):25m16257
The article describes cannabis use at admission as a significant predictor of early psychiatric readmission in young adults with bipolar or psychotic disorders. The full article provides the survival analysis findings summarized in the video, including the time-dependent pattern of risk.
The Sunday Rounds newsletter (October 18, 2026) featured this video as "This Week's Insight". It showed takeaways 1 and 2 above and noted that three more takeaways, Perino's expert commentary, and the full clinical overview are on the site. The newsletter and the website differ on Perino's credential: the newsletter says "PhD" and the website says "MD". This document follows the website.
The accompanying audio is not the original video and is not the AI playback from the Psychiatrist.com page. It is a text-to-speech reading of the video overview and key takeaways text above, generated with a synthetic voice, and has not been reviewed by the authors or by Psychiatrist.com.
This is a summary of an observational, retrospective, single-center study. A retrospective design like this shows an association, not that cannabis causes rehospitalization. The author notes that cannabis use at admission may be a marker of a more severe disease course. For clinical decisions, refer to the full article above.